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Classic hypothyroid symptoms include: Dry, coarse hair Loss of eyebrow hair Puffy face Enlarged thyroid (goiter) Slow heartbeat Constipation Weight gain Brittle nails Arthritis Cold intolerance Depression Dry skin Fatigue Forgetfulness Infertility Muscle aches Heavy periods Classic hyperthyroid symptoms include: Hair loss Bulging eyes Enlarged thyroid (goiter) Sweating Rapid heartbeat Weight loss Frequent bowel movements Warm, moist palms Tremor of fingers Soft nails Difficulty sleeping Heat intolerance Infertility Irritability Muscle weakness Nervousness Scant periods When the thyroid is not functioning properly, there may be an excess or lack of thyroid hormone production, which can lead to hyper- or hypo- thyroidism, respectively