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It can come from lower body weight, lower glycogen, poor hydration, a deeper deficit and worse recovery
This mechanism achieved remarkable efficacy in SURMOUNT-1 [1] , where 2,539 participants [1] lost 20.9% body weight at 72 weeks, with 36% achieving 25% or greater weight loss
known risks include nausea, raised heart rate, pancreatitis, gallbladder disease, and acute kidney injury from dehydration
Oh, and one more thing: it's a so-called fatty alcohol - the good, emollient type of alcohol that is non-drying and non-irritating
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