Given the ingredient categories involved (circulation support, metabolic support, and an adaptogen), taking it sporadically is likely to blunt whatever cumulative effect the formula is designed to build
Over-cleansing can strip natural oils, disrupt the skin barrier, and lead to dryness, sensitivity, and increased oil production
Patients with gastrointestinal disorders such as Crohns disease, celiac disease, or those who have undergone gastrointestinal surgeries (including gastric bypass) often experience impaired B12 absorption
Reported effects in human use are generally mild injection-site reactions, lightheadedness, fatigue, nausea