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Just the levels of quinine found in tonic water may cause potentially fatal immunologically-mediated hypersensitivity reactions, basically like allergic reactions, where it interacts with antibodies to trigger autoimmune reactions that can include chills, fever, a drop in blood pressure, painful bluish discoloration of the hands and feet, and clotting within your blood vessels
On one hand, the clinical benefits are undeniable improved metabolic health, reduced cardiovascular risk, fewer hospitalizations, and lower long-term societal costs
Prescription omega-3 medicines have specific cautions: icosapent ethyl (Vazkepa) has been associated with increased atrial fibrillation risk, while omega-3-acid ethyl esters (Omacor) may increase LDL cholesterol in some patients
That granted the generics leverage to negotiate an entry date before the expiration of the 462 patent, i.e., June 2033
