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The most dramatic results occur between weeks 12 and 48, with continued loss through week 68
While LipRSV reduced oxidative markers in the hippocampus, cerebellum and posterior cortex, the increase observed in the frontal cortex suggests that nanocarrier distribution and local redox balance may critically influence therapeutic outcomes
Am J Clin Nutr 89:2025S-2039S
In vitro studies have found that inhibiting the transcriptional activity of Nrf2 can reduce the synthesis of glutathione, thereby causing the apoptosis of IDH1 mutant cancer cells
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