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Agency Ogilvy
Friedrichsen, M., Breitschaft, A., Tadayon, S., Wizert, A
In preclinical studies, NPI-001 has exhibited the ability to cross blood-brain 1 and blood-retinal 2 barriers
MT-II is a cyclic heptapeptide broadly activating MC1R, MC3R, and MC4R , simultaneously producing melanogenesis alongside central pro-sexual, pro-erectile, and anorectic effects through hypothalamic MC3R/MC4R activation, Cyclisation of the -MSH pharmacophore core is the primary structural determinant of this receptor subtype selectivity shift
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