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Before coming off the medication, the body needs a foundation that can support healthy weight regulation independently
However, as a GLP-1 medicine it slows gastric emptying, which can affect how quickly other oral medicines such as fluoxetine are absorbed, and the tablet must be taken on an empty stomach with a set routine, so the timing of your other medicines needs planning
Semaglutide acts on the GLP-1 receptor alone and tirzepatide on GLP-1 and GIP
Most of what we know comes from animal studies, small case reports and registry data, rather than large clinical studies in humans
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