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Creatine supports ATP regeneration during high-intensity exercise, while L-carnitine supports fatty acid transport and energy metabolism

AG-haESCs (named IG DMR -H19 DMR -AGH-2 or O48 20 ) were used for the generation of Blimp1-T2A-Cre , Trim28 flox , Trim37 MATH , Trim37 RING , and Trim28 K774R+K779R cells

These included oleic acid, quinolinic acid, oxidized glutathione, L-phenylalanine, glutaric acid, N-acetylglucosamine 6-phosphate, malondialdehyde, arachidonic acid, L-lactic acid, uridine 5-diphosphoglucuronic acid, and picolinate, suggesting long-term suppression of lipid metabolism, oxidative stress-related pathways, and intermediates of the kynurenine and glucuronic acid pathways

2015 Jan 1;20:872-91