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While Hurtado advises against discontinuing medication, she noted that dietary, exercise, and behavior support should be offered to everyone throughout their weight loss journey

Medical Writing/Editorial Assistance The authors would like to thank Karen Nunley, PhD (Syneos Health) for medical writing assistance, and Raena Fernandes, MSc, ELS and Aruna Clemente, PhD, (both of Syneos Health) for editorial assistance

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Sites of protease/peptidase vulnerabilities in GLP-1 were removed by amino acid substitution and the peptide backbone was bis-lipidated to promote MEDI7219 reversible plasma protein binding without affecting potency