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45 Interestingly, while UBE1 expression remains unchanged in human heart failure, experimental studies have shown that overexpression of UBE1 or UBE6 in neonatal rat ventricular cardiomyocytes (NRVCMs) increases the ubiquitination of Nav1.5, a major transmembrane protein essential for cardiomyocyte depolarization
Mol Metab 2021;51:101237.ArticlePubMedPMC 10
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Other reports of illegal use of melanocortin analogs have appeared
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