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Impaired Glycination: Glycination is dependent on glyceine-N-acetyltransferase (GLYAT) enzymes and a sufficient amount of glycine, thus, polymorphisms in this gene or insufficient protein intake could impair glycine conjugation
Cysteine is a sulfur amino acid, so in those who can tolerate sulfur foods, consuming sulfur-rich foods, especially those containing the sulfur amino acids, may also support glutathione synthesis
Dysbiosis and intestinal permeability may increase endotoxin, inflammatory signaling and microbial metabolites delivered to the liver
Chinese Pharmacopoeia Commission
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