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It is clear from these findings that while the use of growth factors to treat CNS diseases, such as AD and PD, is a promising strategy, the BBB poses a robust obstacle in turning such strategies into viable treatment options in the clinic

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Her subsequent work with Daniel Drucker using radioimmunoassay and chromatography identified a unique pattern of proglucagon-derived peptides in the gastrointestinal tract and pancreas, including more immunoreactive GLP-1 peptides in GI extracts [18]