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Novel therapeutic opportunities for Alzheimers disease: focus on nonsteroidal anti-inflammatory drugs
GSH in fact is both a nucleophile and a reductant, and therefore can react with electrophilic or oxidizing species rendering the former molecules more soluble and excretable, and the latter unable to interact with more critical cellular constituents such as lipids, nucleic acids and proteins
Glial cells, particularly microglia, are key contributors to neuroinflammation, with microglial activation leading to the production of proinflammatory cytokines like NO, IL-1, and TNF- 42
This can be a disappointing realization for those who have relied on glutathione supplements for skin lightening purposes
