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Such limitations impact the performance of quantitative assays used to assess pharmacodynamics throughout drug development

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was supported by the Instituto de Salud Carlos III (ISCIII) and confounded by the European Regional Development Fund (ERDF), A way to make Europe, grant number PI18/00442 integrated into the State Plan for R & D + I 20172020 and grant number PI21/00343 integrated into the State Plan for R &

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