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it was a randomized, parallel-grouped, phase 2 trial
PMCID: PMC4104274
If you increase your dose every four weeks as per the standard titration schedule, it typically takes about 20 weeks to reach the 15 mg dose
Therefore, for the insulin regimen subgroup analysis, the treatment policy estimand was used to reflect the effect of initiating treatment with oral semaglutide compared with initiating treatment with placebo, both potentially followed by either discontinuation of the trial product and/or initiation of rescue medication
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