Independent predictors of amputation identified in the study included prior amputations, male sex, non-Asian ethnicity, history of PAD, history of neuropathy, albuminuria, and elevated HbA1c levels at baseline.38 While this finding was not replicated in other randomized clinical trials on SGLT-2 inhibitors, it is recommended to conduct a thorough screening for risk factors for amputations when initiating SGLT2 inhibitors
However, research on this pentadecapeptide is primarily animal-based and in vitro , with no published full-text clinical studies despite some authors mentioning a phase 1 trial on BPC-157 as an anti-ulcerative agent in IBD patients [6]
Biochemistry , 3:895, 1964
A Dietitian's Honest Guide Written by Marina Savelyeva, MS, RDN, LD | Medically Reviewed | Updated March 2026 Focus on lean protein, high-fiber vegetables and whole grains, and healthy fats these food groups work alongside GLP-1 medications, not just around them