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Zhai S, Cui Q, Simmons DV, Surmeier DJ (2023) Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in parkinsons disease
The compound was selected from a series of quinolinium-based molecules studied for cell permeability, enzyme selectivity and inhibition of NNMT
PEG incorporation extends circulation, reduces uptake by liver and spleen, and shows no toxicity (Gregoriadis 1995
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