One exception applies when 62323 is used for an implantable infusion pump trial, which is governed by NCD 280.14 instead
Patients experiencing nausea should be advised to: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods that may exacerbate nausea Stay well-hydrated with small, frequent sips of water Consider bland foods such as crackers, toast, or rice during symptomatic periods Avoid lying down immediately after eating For constipation , increasing dietary fibre intake through fruits, vegetables, and whole grains, alongside adequate fluid consumption (1.5-2 litres daily), often provides relief
Clinical trials of TFEB activators such as trehalose (NCT05136885 and NCT05597436) and PPAR agonists such as gemfibrozil (NCT02045056) further illustrate the challenges of translating preclinical findings into clinical benefits
Unlike many therapies that plateau early, weight loss continued throughout treatment