10.1016/j.ebiom.2018.08.035 Summary Keywords Lycopene, digestive precancerous lesions, oxidative stress, inflammatory response, chemoprevention Citation Gan K, Shi W, Liu X, Ding W, Qiu Y and Luo X (2024) Emerging functions of lycopene in the management of digestive premalignant lesions
As an alternative, tributyrin supplementation in diet-induced obese mice was also shown to improve glucose tolerance and inflammatory status (86), indicating that direct supplementation of butyrate might have beneficial effects on both metabolic and inflammatory parameters relevant for the pathophysiology of T2D
In addition, Citrinin can also cause complex translocations with the cellular DNA in a high frequency, and is capable of inducing defects in chromosomal coiling (178), which may lead to the formation of DNA adducts (179)
Okun The New England Journal of Medicines recent publication of a randomized study of a GLP-1 agonist originally designed for diabetes, but applied to Parkinson's disease, has led to a flurry of excitement and to a mountain of questions