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MALE INFERTILITY Research on male factor infertility demonstrates that sperm are vulnerable to reactive oxidative species (ROS) which can result in decreased motility (due to loss of mitochondria ATP production), decreased viability, increased mid-piece morphology, and reduced fertilization (sperm capacitation and acrosome reaction)

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H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH Tesamorelin is modified with a trans-3-hexenoic acid group, which is studied for improving stability and resistance to enzymatic breakdown

Dohil R, Carrigg A, Newbury R (2012) A potential new method to estimate tissue cystine content in nephropathic cystinosis