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Recent advancements in single-cell and spatial transcriptomics, along with proteomics and bioinformatics, have highlighted the intercellular communication between malignant epithelial cells and stromal cells, which is of particular interest for future research (Table 4)
[49] After stopping semaglutide, individuals on average regain 67% of the weight they lost during treatment within the following year, according to a 2025 systematic review
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