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Regardless of barrier penetration, in vivo exposure to microplastics plays a significant role in dopamine neuron degeneration, representing a non-independent risk factor that cannot be overlooked in PD pathogenesis (34).Both in vivo and in vitro experiments demonstrated that Western blotting and immunofluorescence revealed PS-NPs induced pyroptosis, disrupted autophagic flux, and reduced the levels of proteins involved in autophagosome-lysosome fusion
10.1161/STROKEAHA.118.024351 143 KonorevE
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