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For electrophysiological studies, male pathogen-free mice at an age of 618 weeks were used for all experiments

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Features of long-standing lesions include elevation, color variegation, ulceration, and satellite lesions that may have the appearance of physiologic pigmentation

3 The gut microbiota-gut-liver axis: a central hub for dietary nutrient metabolism 3.1 Interactions between the gut microbiota and dietary nutrients 3.1.1 Dietary patterns shape gut microbiota composition The human gastrointestinal tract harbors approximately 100 trillion microbial cells, comprising over 1,000 bacterial species, with a collective genome encoding approximately 150 times more genes than the human genome (26)