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Corban MT, Godo S, Burczak DR, et al
Stomach discomfort is often caused by the breakdown of standard capsules in the acidic environment of the stomach
doi: 10.1016/j.jdiacomp.2020.107641 40
And we deliberately chose exenatide and lixisenatide because they have been used very successfully in the clinic and have a long safety record. Incorporating these GLP-1 therapies into the genome of lettuce also bypasses synthesis challenges faced by oral formulations, such as the need to adjust the stomach acid pH to be less acidic to prevent degradation, he explains
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