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Compounded medications are not reviewed as finished drug products and have not undergone the same review process as approved drugs

This serendipitous discovery redirected the compounds development toward obesity treatment

doi: 10.1172/jci.insight.134270 109 DolletLZierathJR

Additionally, in a 30-day placebo-controlled trial in 300 adults (aged 18-65 years), supplementation with the B vitamins (at doses of about 3 to 13 times the RDA, excluding folic acid), vitamin C (1,000 mg/day), calcium (100 mg/day), and magnesium (100 mg/day) was associated with significant improvements in various scores of psychological stress compared to a placebo (139)