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Beyond its insulinotropic effects, GLP-1R signaling also influences lipid metabolism by modulating hepatic lipid handling and adipose tissue function
But the direction of that impact varies enormously, the timeline of effects matters greatly, and evidence-based interventions exist for those who experience challenges along the way
The following sections summarize some of the most significant and frequently cited research areas, focusing on studies that have shaped the current understanding of this peptide
Rapid weight loss with GLP-1 receptor agonists can also increase the risk of gallstone formation
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