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Topical is the more evidence-supported route, especially for skin endpoints
f , Clinical course, cumulative and maximum score of Arg1 fl/f (n = 18) and Arg1 fl/fl Ccr2 -creER T2 (n = 19) animals subjected to EAE
This doesn't mean harm is certain, but it does mean you cannot extrapolate oral safety data to the IV route" [13]
Injections are administered by registered nurses, not wellness technicians or unlicensed staff
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