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The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology
The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells
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This adverse effect has not yet been clinically reported Hypopigmented patches, especially on sun-exposed areas have been observed after 1012 doses of intravenous injection by practitioners (unpublished observations)
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