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Environmental and behavioral strategies include: Maintaining cooler ambient temperatures and using fans or air conditioning Wearing layered, breathable clothing made from natural fibers like cotton Avoiding known triggers such as spicy foods, caffeine, alcohol, and hot beverages Staying well-hydrated throughout the day Maintaining a healthy sleep environment with cool temperatures and moisture-wicking bedding Evidence-based non-pharmacologic approaches include cognitive behavioral therapy (CBT) and clinical hypnosis, which have demonstrated effectiveness for vasomotor symptoms

Instead of working on blood flow alone, PT-141 acts on the brains melanocortin system

What a Responsible Clinician Can Say About This Finding A responsible clinician can now say, with real evidentiary backing, that the human neuroimaging literature on CBD and anxiety is small, heterogeneous, and has not produced a consistent regional or network-level signature, despite individual studies reporting amygdala-related changes

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