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NAION occurs at an estimated rate of 2.3-10.2 per 100,000 people in the United States above the age of 50

Through this mechanism, Saxenda: Slows gastric emptying , which prolongs the feeling of fullness after meals Reduces appetite by acting on appetite centres in the hypothalamus Enhances glucose-dependent insulin secretion from pancreatic beta cells Suppresses inappropriate glucagon secretion when blood glucose levels are elevated These combined effects lead to reduced calorie intake and, consequently, weight loss

Even after approval, manufacturing ramp-up and commercial launch logistics mean CagriSema likely will not be widely available to patients until the following year

The groups with inconsistent results skip steps