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Semaglutide improves type 2 diabetes glucose management

The MHRA-approved starting dose is 0.25 mg weekly for 4 weeks (to minimise gastrointestinal side effects), then increased to 0.5 mg weekly

Orthostatic considerations Orthostatic hypotension (a drop of 20 mmHg systolic or 10 mmHg diastolic on standing) can develop during early treatment for several reasons: Reduced fluid intake from nausea Reduced sodium intake from decreased eating Continued full-dose antihypertensive medications as BP drops Volume contraction from weight loss Patients should be counseled to rise slowly, maintain hydration, and contact their clinician if they experience dizziness on standing

If you forget a dose, its important to know what to do