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The results of SURPASS-6 further support the role of Tirzepatide in treatment of individuals with type 2 on insulin and obesity. The primary goal of the trial was to determine if tirzepatide was as safe and effective as fast-acting insulin in lowering A1C over 52 weeks

Most experienced users recommend starting at 0.25 mg daily for the first week, then increasing to 0.5 mg daily if well tolerated and additional benefit seems likely