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Most Americans have some degree of gut compromise from processed food, antibiotic history, chronic stress, or environmental toxins
Patients with contraindications - including personal or family history of medullary thyroid carcinoma or MEN 2 syndrome, pancreatitis history, severe GI or kidney disease, pregnancy, or breastfeeding - won't be approved
Blood 139 , 584596 (2022)
Beyond that range, most clinicians would consider use to be more sustained
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