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It has been suggested that metformin displays potential beneficial effects by reducing several cardiovascular dysfunction risk factors, such as body mass index (BMI) (MD: 0.53 kg/m 2 , 95% CI 0.95, 0.12), insulin-resistance (HOMA-IR) (MD:0.50, 95% CI 0.91, 0.09), triglyceride (MD: 0.11 mmol/L, 95% CI 0.20, 0.02), plasma plasminogen activator inhibitor-1 (Ruth, Day et al.) (MD: 4.99 ng/mL, 95% CI 6.78, 3.21) (Li and Li, 2023), carotid intima-media thickness (CIMT), and flow-mediated dilation (FMD) (Wang et al., 2024) in PCOS patients

Focus on incorporating some strength training into your exercise routine

You should make sure you include: Fresh fruits and vegetables Lean proteins Fibre Whole grains Try to avoid High amounts of sugar High amounts of saturated fats If you're experiencing nausea as a side effect, foods with strong tastes or smells Bear in mind that Xenical will only work if your diet includes fat

Instead, most people notice that hunger becomes quieter and easier to manage within the first 13 weeks