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Many participants experienced substantial improvement in their OSA severity classification, though complete remission rates varied and should be assessed through follow-up sleep studies

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The deadline for stopping production and distribution of compounded tirzepatide passed in March

Bulk RNA Seq RNA quality was determined by RNA integrity number with Agilent Technologies 2100 Bioanalyzer (Cat #5067-1511), to confirm that all samples had an RNA integrity number exceeding 9 and were deemed suitable for further analysis