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Here we report the surprising finding that a clinically validated and tunable self-therapeutic ultrasmall silica nanoparticle prolongs survival in a highly resistant melanoma model in combination with interleukin-6 and PD-L1 inhibition through activation of the stimulator of interferon genes/interleukin-6/PD-L1 axis and reprogramming of the tumour microenvironment towards a pro-inflammatory phenotype
If you're working on something similar or have feedback on the architecture, I'd love to hear it in the comments.
However, this is not the same as taking a prescription GLP-1 medicine
doi: 10.1016/j.metabol.2016.04.004 187 GastaldelliACusiK
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