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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

Samples not presenting these positive internal controls were excluded

doi: 10.1007/s10753-020-01233-w 168 LinC.-Y.YaoC.-A

Diese Begrenzung ist nicht durch pharmakokinetische Akkumulation begrndet BPC-157 baut sich nicht kumulativ auf sondern durch das pragmatische Vorsichtsprinzip bei einer Substanz mit begrenzten humanen Langzeitdaten