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However, exercise caution when working out in the summer heat
ROS homeostasis plays a vital role in organismal balance and physiological processes [100]
Jon Napitupulu is Director of Media Relations at The Clinical Trial Vanguard
Even though the immune system responds towards inflammatory stimuli through ROS, increased ROS levels can damage DNA, proteins, and lipids, and result in activating various signaling pathways (such as NF-B and mitogen-activated protein kinase (MAPK)), stimulating T helper cells 1 (Th1) and Th17 cells, and promoting the release of inflammatory cytokines (Plenkowska et al., 2020), which can contribute to the development and exacerbation of the psoriatic inflammation
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