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What to watch for: Acid reflux is a known GLP-1 side effect and grapefruit's pH is around 3.0, which is acidic enough to irritate an already-inflamed esophagus

We further observed that the lead GSTO1 inhibitor C1-27 blocked cancer cell proliferation, caused cytotoxicity, inhibited cell cycle progression and increased the sensitivity of cancer cells to cisplatin

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Upscaling to 5-L bioreactors revealed distinct substrate utilization patterns, achieving complete TPA depletion within 23 h (q TPA = 0.45 g/gCDW/h) compared to extended EG consumption (q EG = 0.13 g/gCDW/h)