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doi: 10.1016/j.jff.2022.105384
GLP-1 receptor agonists have been shown in multiple studies to exert anti-inflammatory effects, including inhibition of monocyte chemotaxis, suppression of macrophage inflammatory responses, and AMPK-mediated downregulation of the NF-B signaling pathway, thereby reducing systemic inflammation (36)
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Chronic stress elevates cortisol, which initially suppresses immune function but eventually leads to cortisol resistance and rebound inflammation
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