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Tirzepatide, like other GLP-1s, delay gastric emptying and increase feelings of fullness, which help to reduce appetite and, therefore, food intake
Yes, it is low in calories and helps reduce unhealthy cravings when consumed without added sugar
Gastrointestinal side effects like nausea can reduce fluid intake, leading to dehydration and orthostatic hypotension
Whether this unique pattern worsens the obese state or constitutes a favorable adaptation remains unclear, and the physiological and pathophysiological implications of the altered GH/IGF-I axis in obesity remain uncertain with GH neither being the cause nor the solution to reverse obesity
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