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3) ECM remodeling and dermal architecture: GHK-Cu stimulates collagen, elastin, proteoglycans, and glycosaminoglycans, while synchronously increasing matrix metalloproteinases (and their inhibitors) to clear damaged ECM actions that can "reset" the perifollicular stroma and support dermal papilla function
Welsh, W
Because cysteine is the least abundant of the three precursors in most physiological settings, cysteine availability is the principal bottleneck for GSH synthesis -- which is precisely the leverage point NAC addresses as a precursor
