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The reasons cited by the FDA included concerns about immunogenicity, peptide impurity characterization challenges, and the lack of adequate safety data from human clinical trials

and Americans views of drugs used for weight loss, drawn from Pew Research Center surveys and other sources

Tirzepatide drugs like Zepbound continue to cause severe injuries, like vision loss, pancreatitis, blood clots, and a range of serious gastrointestinal injuries, in some patients