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In the absence of transition metals, ascorbic acid can diminish the incidence of mutations caused by H 2 O 2 in human cells [165]

An Other factors that can contribute to vitamins losing potency include: extreme temperatures exposure to light exposure to oxygen pH levels Unopened vitamin supplements are more likely to retain their potency because moisture, light, and oxygen are less likely to affect them

Note that initial evaluation for Wegovy actually began on the 31st of March, 2021 according to the TGA , but this didnt specify proposed application methods or dosages