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Research indicates that combining adequate protein intake with resistance exercise during weight loss optimises body composition changes, maximising fat loss whilst preserving or even increasing lean mass

and for patients receiving placebo, -0.2%

To streamline the process, gather recent lab work (fasting glucose, HbA1c, lipid panel, kidney function), a list of previously tried medications and dosages, and any comorbidities such as cardiovascular disease or hypertension