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In addition to their cardiovascular benefits, GLP-1 RAs also confer renal protection, demonstrating a 19% reduction in composite renal outcomes, a 16% reduction in end-stage kidney disease, a 21% reduction in kidney function decline [6]

How you take it (water only, empty stomach, wait 30 minutes) is not optional trivia, its literally in the label

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Selected Data 1) The study conducted by researchers Tukhovskaya et al aimed to investigate the neuroprotective and motor function recovery effects of intranasal Delta Sleep-Inducing Peptide (DSIP) in Sprague-Dawley (SD) rats subjected to focal stroke induced by middle cerebral artery occlusion (MCAO)