Recombinant Human Growth Regulated Protein-alpha/CXCL1 (Human GRO-α/CXCL1)_C230363 Size:100 μg is an 8 kDa proinflammatory

is an 8 kDa proinflammatory member of the CXC chemokine family

The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1 ng/ml

> 90 % by SDS-PAGE  analyses

Ligation triggers receptor dimerization

Recombinant Human Growth Regulated Protein-alpha/CXCL1 (Human GRO-α/CXCL1)_C230363 Size:100 μg is an 8 kDa proinflammatoryCXCL1, also known as KC, GRO alpha, and CINC 1, is an approximately 8 kDaproinflammatorychemokine that plays a key role in neutrophil migration and activation. Mature human CXCL1 shares 64% and 67% aa sequence identity with mouse and rat CXCL1, respectively. It is produced by many cell types in inflammatory sites and during chronic inflammatory diseases. CXCL1 can associate into bioactive dimers and primarily signals through CXCR2 IL 8 RB but can also