Recombinant Human Heparin-binding EGF-like Growth Factor (Human HB-EGF)_C230367 Size:100 μg including a 28 amino acid

including a 28 amino acid cytoplasmic region

while aa 1 and 2 (Lys- Pro) are involved in receptor activation

It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four alpha -helix structure

Avoid repeated freeze-thaw cycles

Recombinant Human Heparin-binding EGF-like Growth Factor (Human HB-EGF)_C230367 Size:100 μg including a 28 amino acidHuman HB EGF (Heparin Binding EGF like growth factor), also known as the DTR (diphtheria toxin receptor), is a 12 16 kDa member of the EGF family of peptide growth factors. It is further classified as a group 2 ErbB ligand based on its ability to activate both the EGF ErbB1 and ErbB4 receptors. Mature HB EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. The transmembrane form of HBEGF is a juxtacrine growth