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In patients with treatment-resistant depression, naltrexone 50 mg blocked the antidepressant but not the dissociative effects of KET, suggesting that the opioid system may also be required for KET antidepressant activities (Williams et al., 2018)
Semaglutide stimulates glucose-dependent insulin secretion, meaning it triggers insulin release when blood glucose is elevated but does not cause problematic hypoglycemia in people without diabetes because it stops working when glucose normalizes
Calcium flux in HEK293 cells was measured as previously described [26]
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