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Indeed, undifferentiated TC cells express low levels of sodium/iodine-symporter (NIS), a protein membrane crucial for iodine uptake by thyrocites and consequently essential for the efficacy of RAI, the most effective therapy for TC in case of not complete surgical removal
Julie Paik, associate professor of medicine in the Division of Pharmacoepidemiology and Pharmacoeconomics and the Division of Renal (Kidney) Medicine at Brigham and Womens Hospital in Boston, MA, and corresponding author of this study, said her research group decided to examine SGLT2 inhibitors as a possible way to lower kidney stone risk because they had already been studying this newer class of diabetes medications for several years
Both formulations contain the same active ingredient but differ in dosing protocols and FDA-approved indications
That is why the guidance focuses on change rather than on appearance
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